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Methotrexate Sodium Injection

FDA shortage status · Source checked 2026-08-22T15:54:11+00:00

Status

FDA currently lists this ingredient in shortage.

This is nationwide FDA status, not local pharmacy inventory. CiteFacts does not provide medical, treatment, substitution, or dosing advice.

FDA package and manufacturer records

CompanyPresentationFDA availability fieldFDA update
Accord Healthcare Inc.Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 16729-277-30)Available08/17/2026
Accord Healthcare Inc.Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 16729-277-35)Available08/17/2026
Fresenius Kabi USA, LLCMethotrexate Preservative Free, Injection, 1 g (NDC 63323-122-50)Available08/04/2026
Fresenius Kabi USA, LLCMethotrexate Sodium, Injection, 25 mg/1 mL (NDC 63323-123-10)Available08/04/2026
Hikma Pharmaceuticals USA, Inc.Methotrexate, Preservative Free, Injection, 1 g (NDC 0143-9830-01)Unavailable08/13/2026
Hikma Pharmaceuticals USA, Inc.Methotrexate, Preservative Free, Injection, 25 mg/1 mL (NDC 0143-9519-10)Available08/13/2026
Hospira, Inc., a Pfizer CompanyMethotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-124-40)Available08/07/2026
Hospira, Inc., a Pfizer CompanyMethotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-408-25)Available08/07/2026
Hospira, Inc., a Pfizer CompanyMethotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-408-41)Available08/07/2026
Hospira, Inc., a Pfizer CompanyMethotrexate Sodium, Injection, 50 mg/2 mL (25 mg/mL) (NDC 61703-350-10)Available08/07/2026
Hospira, Inc., a Pfizer CompanyMethotrexate Sodium, Injection, 50 mg/2 mL (25 mg/mL) (NDC 61703-350-38)Available08/07/2026
Teva Pharmaceuticals USA, Inc.Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3671-01)Unavailable08/17/2026
Teva Pharmaceuticals USA, Inc.Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3675-01)Unavailable08/17/2026
Teva Pharmaceuticals USA, Inc.Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3678-01)Unavailable08/17/2026

Source facts

Grouped generic ingredient: Methotrexate Sodium Injection · 14 package records · Latest FDA row update: 08/17/2026

Therapeutic categories: Oncology, Rheumatology
Dosage forms: Injection
Routes: INTRA-ARTERIAL, INTRAMUSCULAR, INTRATHECAL, INTRAVENOUS, SUBCUTANEOUS

Open FDA source data · JSON · Markdown

FDA is authoritative. Source retrieved 2026-08-22T15:54:11+00:00. Derived grouping is documented in this record's derivations.