{
  "schema_version": "0.1.0",
  "id": "fda-drug-shortage:sodium-bicarbonate-injection",
  "slug": "sodium-bicarbonate-injection",
  "title": "FDA shortage status: Sodium Bicarbonate Injection",
  "ingredient": "Sodium Bicarbonate Injection",
  "status": "current",
  "source_statuses": [
    "Current",
    "To Be Discontinued"
  ],
  "brand_names": [
    "SODIUM BICARBONATE"
  ],
  "therapeutic_categories": [
    "Endocrinology/Metabolism",
    "Gastroenterology",
    "Pediatric"
  ],
  "dosage_forms": [
    "Injection"
  ],
  "routes": [
    "INTRAVENOUS"
  ],
  "package_count": 19,
  "packages": [
    {
      "package_ndc": "76329-3352-1",
      "product_ndc": "76329-3352",
      "company_name": "Amphastar Pharmaceuticals, Inc.",
      "manufacturer_name": "International Medication Systems, Limited",
      "presentation": "Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 76329-3352-1)",
      "availability": "Limited Availability",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/18/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "51754-5012-4",
      "product_ndc": "51754-5001",
      "company_name": "Exela Pharma Sciences, LLC",
      "manufacturer_name": "Exela Pharma Sciences, LLC",
      "presentation": "Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 51754-5012-4)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "07/22/2026",
      "initial_posting_date": "07/24/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "51754-5001-5",
      "product_ndc": "51754-5001",
      "company_name": "Exela Pharma Sciences, LLC",
      "manufacturer_name": "Exela Pharma Sciences, LLC",
      "presentation": "Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5001-5)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "07/22/2026",
      "initial_posting_date": "07/24/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "51754-5011-4",
      "product_ndc": "51754-5001",
      "company_name": "Exela Pharma Sciences, LLC",
      "manufacturer_name": "Exela Pharma Sciences, LLC",
      "presentation": "Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5011-4)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "07/22/2026",
      "initial_posting_date": "07/24/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-083-05",
      "product_ndc": "63323-083",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 63323-083-05)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "07/24/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-089-50",
      "product_ndc": "63323-083",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 63323-089-50)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "07/24/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-4900-14",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Sodium Bicarbonate, Injection, 10 mEq/10 mL (8.4%, 1 mEq/mL) Syringes (NDC 0409-4900-14)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-5555-01",
      "product_ndc": "0409-5555",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-01)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-5555-02",
      "product_ndc": "0409-5555",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-02)",
      "availability": "Limited Availability",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-5534-14",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 0409-5534-14)",
      "availability": null,
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "11/07/2025",
      "initial_posting_date": "11/07/2025",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-4916-14",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Sodium Bicarbonate, Injection, 44.6 mEq/50 mL (7.5%, 0.9 mEq/mL) Syringes (NDC 0409-4916-14)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-5534-14",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Sodium Bicarbonate, Injection, 5 mEq/10 mL (4.2%, 0.5 mEq/mL) Syringes (NDC 0409-5534-14)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-6625-14",
      "product_ndc": "0409-6625",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-14)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-6625-35",
      "product_ndc": "0409-6625",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-35)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-6637-14",
      "product_ndc": "0409-4916",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) Syringes (NDC 0409-6637-14)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-4916-14",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Sodium Bicarbonate, Injection, 75 mg/1 mL (NDC 0409-4916-14)",
      "availability": null,
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "11/07/2025",
      "initial_posting_date": "11/07/2025",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-4900-14",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-4900-14)",
      "availability": null,
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "11/07/2025",
      "initial_posting_date": "11/07/2025",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-6637-14",
      "product_ndc": "0409-4916",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-6637-14)",
      "availability": null,
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "11/07/2025",
      "initial_posting_date": "11/07/2025",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "81298-7620-3",
      "product_ndc": "81298-7620",
      "company_name": "Long Grove Pharmaceuticals LLC",
      "manufacturer_name": "Long Grove Pharmaceuticals, LLC",
      "presentation": "Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 81298-7620-3)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/17/2026",
      "initial_posting_date": "03/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    }
  ],
  "availability_counts": {
    "Available": 7,
    "Limited Availability": 2,
    "Unavailable": 6
  },
  "initial_posting_date": "03/01/2017",
  "latest_source_update": "11/07/2025",
  "source_updated_at": "2026-08-22",
  "official_url": "https://api.fda.gov/drug/shortages.json",
  "source_name": "U.S. Food and Drug Administration openFDA Drug Shortages",
  "source_license_url": "https://open.fda.gov/license/",
  "retrieved_at": "2026-08-22T15:54:11+00:00",
  "unknowns": {
    "local_availability": "Unknown. FDA status is nationwide and is not local inventory.",
    "clinical_alternatives": "Not provided. CiteFacts does not publish treatment or substitution advice.",
    "resolution_date": "Unknown unless an FDA source row provides an update date."
  },
  "derivations": {
    "status": "current when a grouped FDA row has Current; otherwise it preserves the available FDA Resolved, Discontinuation, or not-current state.",
    "ingredient_page": "Grouped by FDA generic_name, falling back to openFDA.generic_name.",
    "availability_counts": "Count of non-empty FDA package availability values; it is not a claim about local supply."
  }
}