{
  "schema_version": "0.1.0",
  "id": "fda-drug-shortage:morphine-sulfate-injection",
  "slug": "morphine-sulfate-injection",
  "title": "FDA shortage status: Morphine Sulfate Injection",
  "ingredient": "Morphine Sulfate Injection",
  "status": "current",
  "source_statuses": [
    "Current"
  ],
  "brand_names": [
    "DURAMORPH",
    "INFUMORPH 200",
    "INFUMORPH 500",
    "MITIGO",
    "MORPHINE SULFATE"
  ],
  "therapeutic_categories": [
    "Analgesia/Addiction"
  ],
  "dosage_forms": [
    "Injection"
  ],
  "routes": [
    "EPIDURAL",
    "INTRAMUSCULAR",
    "INTRATHECAL",
    "INTRAVENOUS"
  ],
  "package_count": 24,
  "packages": [
    {
      "package_ndc": "76329-1912-1",
      "product_ndc": "76329-1912",
      "company_name": "Amphastar Pharmaceuticals, Inc.",
      "manufacturer_name": "International Medication Systems, Limited",
      "presentation": "Morphine Sulfate, Injection, 1 mg/1 mL (NDC 76329-1912-1)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/18/2026",
      "initial_posting_date": "12/06/2018",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-451-01",
      "product_ndc": "63323-451",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Morphine Sulfate, Injection, 10 mg/1 mL (NDC 63323-451-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-452-01",
      "product_ndc": "63323-451",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Morphine Sulfate, Injection, 2 mg/1 mL (NDC 63323-452-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "76045-004-11",
      "product_ndc": "76045-004",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi, USA LLC",
      "presentation": "Morphine Sulfate, Injection, 2 mg/1 mL (NDC 76045-004-11)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-454-01",
      "product_ndc": "63323-451",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Morphine Sulfate, Injection, 4 mg/1 mL (NDC 63323-454-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "76045-005-11",
      "product_ndc": "76045-004",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi, USA LLC",
      "presentation": "Morphine Sulfate, Injection, 4 mg/1 mL (NDC 76045-005-11)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-455-01",
      "product_ndc": "63323-451",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Morphine Sulfate, Injection, 5 mg/1 mL (NDC 63323-455-01)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6020-10",
      "product_ndc": "0641-6019",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Duramorph, Injection, .5 mg/1 mL (NDC 0641-6020-10)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL",
        "INTRAVENOUS"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6019-10",
      "product_ndc": "0641-6019",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Duramorph, Injection, 1 mg/1 mL (NDC 0641-6019-10)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL",
        "INTRAVENOUS"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6039-01",
      "product_ndc": "0641-6039",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Infumorph 200 (Preservative-Free Morphine Sulfate Sterile Solution), Injection, 10 mg/1 mL (NDC 0641-6039-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6040-01",
      "product_ndc": "0641-6039",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Infumorph 500 (Preservative-Free Morphine Sulfate Sterile Solution), Injection, 25 mg/1 mL (NDC 0641-6040-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6127-25",
      "product_ndc": "0641-6125",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Morphine Sulfate, Injection, 10 mg/1 mL (NDC 0641-6127-25)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6125-25",
      "product_ndc": "0641-6125",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Morphine Sulfate, Injection, 4 mg/1 mL (NDC 0641-6125-25)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6126-25",
      "product_ndc": "0641-6125",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Morphine Sulfate, Injection, 8 mg/1 mL (NDC 0641-6126-25)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1893-01",
      "product_ndc": "0409-1890",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Morphine Sulfate, Injection, 10 mg/1 mL Syringes (NDC 0409-1893-01)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-3815-12",
      "product_ndc": "0409-3814",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Morphine Sulfate, Injection, 10 mg/10 mL (1 mg/mL) (NDC 0409-3815-12)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL",
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1890-01",
      "product_ndc": "0409-1890",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Morphine Sulfate, Injection, 2 mg/1 mL Syringes (NDC 0409-1890-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1891-01",
      "product_ndc": "0409-1890",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Morphine Sulfate, Injection, 4 mg/1 mL Syringes (NDC 0409-1891-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-3814-12",
      "product_ndc": "0409-3814",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Morphine Sulfate, Injection, 5 mg/10 mL (0.5 mg/mL) (NDC 0409-3814-12)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL",
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1134-05",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Morphine Sulfate, Injection, 50 mg/1 mL (NDC 0409-1134-05)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1896-20",
      "product_ndc": "0409-1896",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Morphine Sulfate, Injection, 50 mg/1 mL (NDC 0409-1896-20)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAVENOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1892-01",
      "product_ndc": null,
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": null,
      "presentation": "Morphine Sulfate, Injection, 8 mg/1 mL Syringes (NDC 0409-1892-01)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "66794-160-02",
      "product_ndc": "66794-160",
      "company_name": "Piramal Critical Care Inc.",
      "manufacturer_name": "Piramal Critical Care, Inc.",
      "presentation": "Mitigo, Injection, 200 mg/20 mL (NDC 66794-160-02)",
      "availability": "Limited Availability",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "66794-162-02",
      "product_ndc": "66794-160",
      "company_name": "Piramal Critical Care Inc.",
      "manufacturer_name": "Piramal Critical Care, Inc.",
      "presentation": "Mitigo, Injection, 500 mg/20 mL (NDC 66794-162-02)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "EPIDURAL",
        "INTRATHECAL"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    }
  ],
  "availability_counts": {
    "Available": 16,
    "Limited Availability": 1,
    "Unavailable": 7
  },
  "initial_posting_date": "10/31/2017",
  "latest_source_update": "08/18/2026",
  "source_updated_at": "2026-08-22",
  "official_url": "https://api.fda.gov/drug/shortages.json",
  "source_name": "U.S. Food and Drug Administration openFDA Drug Shortages",
  "source_license_url": "https://open.fda.gov/license/",
  "retrieved_at": "2026-08-22T15:54:11+00:00",
  "unknowns": {
    "local_availability": "Unknown. FDA status is nationwide and is not local inventory.",
    "clinical_alternatives": "Not provided. CiteFacts does not publish treatment or substitution advice.",
    "resolution_date": "Unknown unless an FDA source row provides an update date."
  },
  "derivations": {
    "status": "current when a grouped FDA row has Current; otherwise it preserves the available FDA Resolved, Discontinuation, or not-current state.",
    "ingredient_page": "Grouped by FDA generic_name, falling back to openFDA.generic_name.",
    "availability_counts": "Count of non-empty FDA package availability values; it is not a claim about local supply."
  }
}