{
  "schema_version": "0.1.0",
  "id": "fda-drug-shortage:hydromorphone-hydrochloride-injection",
  "slug": "hydromorphone-hydrochloride-injection",
  "title": "FDA shortage status: Hydromorphone Hydrochloride Injection",
  "ingredient": "Hydromorphone Hydrochloride Injection",
  "status": "current",
  "source_statuses": [
    "Current"
  ],
  "brand_names": [
    "DILAUDID",
    "HYDROMORPHONE HYDROCHLORIDE"
  ],
  "therapeutic_categories": [
    "Analgesia/Addiction"
  ],
  "dosage_forms": [
    "Injection"
  ],
  "routes": [
    "INTRAMUSCULAR",
    "INTRAVENOUS",
    "SUBCUTANEOUS"
  ],
  "package_count": 26,
  "packages": [
    {
      "package_ndc": "76045-121-11",
      "product_ndc": "76045-009",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Dilaudid, Injection, .2 mg/1 mL (NDC 76045-121-11)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "76045-009-06",
      "product_ndc": "76045-009",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Dilaudid, Injection, 1 mg/1 mL (NDC 76045-009-06)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "76045-009-11",
      "product_ndc": "76045-009",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Dilaudid, Injection, 1 mg/1 mL (NDC 76045-009-11)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "76045-010-11",
      "product_ndc": "76045-009",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Dilaudid, Injection, 2 mg/1 mL (NDC 76045-010-11)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-852-25",
      "product_ndc": "63323-851",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Hydromorphone Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-852-25)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-851-10",
      "product_ndc": "63323-851",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (NDC 63323-851-10)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-851-15",
      "product_ndc": "63323-851",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (NDC 63323-851-15)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-851-50",
      "product_ndc": "63323-851",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (NDC 63323-851-50)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-853-25",
      "product_ndc": "63323-851",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (NDC 63323-853-25)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "63323-854-10",
      "product_ndc": "63323-851",
      "company_name": "Fresenius Kabi USA, LLC",
      "manufacturer_name": "Fresenius Kabi USA, LLC",
      "presentation": "Hydromorphone Hydrochloride, Injection, 4 mg/1 mL (NDC 63323-854-10)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/04/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-0121-25",
      "product_ndc": null,
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": null,
      "presentation": "Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (NDC 0641-0121-25)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/03/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0641-6254-01",
      "product_ndc": "0641-6254",
      "company_name": "Hikma Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Hikma Pharmaceuticals USA Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (NDC 0641-6254-01)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/13/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1805-01",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 0.25 mg/ 0.5 mL NexJect\u2122 Single-dose Syringe Luer Lock (no needle) (NDC 0409-1805-01)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-4264-01",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 0.5 mg/0.5 mL NexJect\u2122 Single-dose Syringe Luer Lock (no needle) (NDC 0409-4264-01)",
      "availability": "Limited Availability",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1283-37",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 1 mg/1 mL (NDC 0409-1283-37)",
      "availability": "Unavailable",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1283-31",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 1 mg/1 mL Syringes (NDC 0409-1283-31)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-2634-01",
      "product_ndc": "0409-2634",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (NDC 0409-2634-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1312-36",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (NDC 0409-1312-36)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-3365-10",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (NDC 0409-3365-10)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1312-30",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 2 mg/1 mL Syringes (NDC 0409-1312-30)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-1304-31",
      "product_ndc": "0409-1283",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 4 mg/1 mL Syringes (NDC 0409-1304-31)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-2634-05",
      "product_ndc": "0409-2634",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 50 mg/5 mL (10 mg/mL) (NDC 0409-2634-05)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0409-2634-50",
      "product_ndc": "0409-2634",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "manufacturer_name": "Hospira, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 500 mg/50 mL (10 mg/mL) (NDC 0409-2634-50)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/07/2026",
      "initial_posting_date": "10/31/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0703-0018-01",
      "product_ndc": "0703-0018",
      "company_name": "Teva Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Teva Parenteral Medicines, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (NDC 0703-0018-01)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/17/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0703-0110-03",
      "product_ndc": "0703-0018",
      "company_name": "Teva Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Teva Parenteral Medicines, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (NDC 0703-0110-03)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/17/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    },
    {
      "package_ndc": "0703-0113-03",
      "product_ndc": "0703-0018",
      "company_name": "Teva Pharmaceuticals USA, Inc.",
      "manufacturer_name": "Teva Parenteral Medicines, Inc.",
      "presentation": "Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (NDC 0703-0113-03)",
      "availability": "Available",
      "dosage_form": "Injection",
      "routes": [
        "INTRAMUSCULAR",
        "INTRAVENOUS",
        "SUBCUTANEOUS"
      ],
      "update_date": "08/17/2026",
      "initial_posting_date": "11/01/2017",
      "source_url": "https://api.fda.gov/drug/shortages.json"
    }
  ],
  "availability_counts": {
    "Available": 18,
    "Limited Availability": 1,
    "Unavailable": 7
  },
  "initial_posting_date": "10/31/2017",
  "latest_source_update": "08/17/2026",
  "source_updated_at": "2026-08-22",
  "official_url": "https://api.fda.gov/drug/shortages.json",
  "source_name": "U.S. Food and Drug Administration openFDA Drug Shortages",
  "source_license_url": "https://open.fda.gov/license/",
  "retrieved_at": "2026-08-22T15:54:11+00:00",
  "unknowns": {
    "local_availability": "Unknown. FDA status is nationwide and is not local inventory.",
    "clinical_alternatives": "Not provided. CiteFacts does not publish treatment or substitution advice.",
    "resolution_date": "Unknown unless an FDA source row provides an update date."
  },
  "derivations": {
    "status": "current when a grouped FDA row has Current; otherwise it preserves the available FDA Resolved, Discontinuation, or not-current state.",
    "ingredient_page": "Grouped by FDA generic_name, falling back to openFDA.generic_name.",
    "availability_counts": "Count of non-empty FDA package availability values; it is not a claim about local supply."
  }
}